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Although Power Custom Fields does not currently have REST API support, it is possible to set values for fields using Jira’s REST API. To do this, you need to use the following syntax:

• For multiple values fields:

{"label1":"","value":"10000"}#|#{"label2":"","value":"10001"}

• For single values fields:

{"label": "Some label", "value": "some_value"}

Here you can see is an example of how to set a field’s value: https://docs.atlassian.com/software/jira/docs/api/REST/7.6.1/#api/2/issue-editIssue  NoteThe REST API field value you provide should be a JSON string in the given format. If the syntax is not respected, the field will not render properly.